Istin is used for the treatment of high blood pressure or a certain type of chest pain called angina.
Istin contains the active ingredient amlodipine, which belongs to the group of medicines called calcium antagonists.
In patients suffering from high blood pressure, Istin works by causing blood vessels to relax, which allow the blood to pass through more easily.
In patients with angina, this medication works by improving the supply of blood to the heart muscle which ten receives more oxygen and as result, chest pain is prevented and relieved. Istin does not provide immediate relief of chest pain from angina.
The main benefit of using Istin is its ability to lower blood pressure and relieve the chest pain called angina.
Always take Istin exactly as your doctor or pharmacist has told you. Check with your doctor if you are not sure.
Istin is to be taken by mouth before or after a meal or a drink. It is recommended that you take Istin at approximately the same time each day with a drink of water. Do not take this medicine with grapefruit juice.
If you forget to take a tablet as scheduled, leave it out completely. Take your next dose at the right time. Do not take a double dose to make up for a forgotten dose.
Your doctor will advise you how long to take this medicine. Your condition may return if you stop using this medicine before you are advised.
If you have questions on the use of this medicine, ask your doctor or your pharmacist.
The recommended initial dose of Istin for adults is 5 mg once daily. The dose can be increased to Istin 10 mg once daily.
For children and adolescents (6-17 years old), the recommended starting dose is 2.5 mg once daily. The maximum recommended dose is 5 mg a day. Istin 5 mg tablets can be divided into halves to provide a 2.5 mg dose.
As with all medicines, Istin can cause some unwanted side effects, although not everyone who uses the medicine gets them.
See your doctor immediately if you experience any of the following side effects after taking Istin:
A very common side effect of Istin is oedema.
The following are common side effects of Istin:
The following are the uncommon side effects of using Istin:
In very rare cases, a person may have confusion as a result of the use of this medication.
Do not take Istin if:
Before you start using Istin, let your doctor know if you have the following conditions:
Istin should not be used in children under the age of 6. It should be used only for hypertension in children and adolescents from 6 years to 17 years of age.
Grapefruit juice and grapefruit should not be consumed by those are taking Istin. Grapefruit and grapefruit juice can lead to an increase in the blood levels of amlodipine, which can lead to an unpredictable increase in the blood pressure lowering effect of this medication.
Istin may affect your ability to drive a vehicle or operate machinery. If the medication makes you feel dizzy, sick, or tired, or gives you a headache, do not drive or operate machinery and contact your doctor immediately.
The safety of Istin in human pregnancy has not been established. If you think you might be pregnant, or are planning to get pregnant, you must consult your doctor before you start taking Istin.
Amlodipine has been known to pass into breast milk in small amounts. If you are breastfeeding or about to start breastfeeding, you must consult your doctor before taking Istin.
Istin is not known to significantly interact with any other medicines, but it is still important that you share with your doctor a list of all the medications you are currently taking. Do not start taking a new medication while taking Istin without first informing your doctor.
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