Simvastatin is a cholesterol-lowering drug. It belongs to a class of drugs called HMG-CoA reductase inhibitors or statins. It is used to lower cholesterol and triglycerides in the blood.
Simvastatin is also used to lower the risk of stroke, heart attack, and other complications in people with diabetes, coronary heart disease, or other risk factors.
Simvastatin is used in adult and children who are 10 years or older.
Simvastatin works by reducing the volume of cholesterol made by the liver. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.
In addition to eating a proper diet, other lifestyle changes that may help this medication work better include losing weight, exercising, and stopping smoking. You can ask your doctor for more details.
The main benefit of taking Simvastatin is lowering bad cholesterol and triglycerides in the blood while raising the levels of good cholesterol. Both actions contribute to the lessening of the risk of heart disease and help prevent strokes and heart attack.
Take Simvastatin by mouth as directed by your doctor, usually once daily in the evening. If you are using the tablet form of Simvastatin, you take it with or without a meal.
If you are using the liquid form of this medication, take it in an empty stomach. Shake the bottle well at least for 20 seconds before each dose. Carefully measure the dose by using a special measuring device or spoon. Do not use a household spoon because you may not get the correct dose.
Your dosage of Simvastatin is based on your medical condition, response to the treatment, age, and other medications you may be taking. Tell your doctor all the medicines you are currently taking.
The usual maximum dose for Simvastatin is 40 mg per day. If you have been instructed by your doctor to take more than 40 mg, continue with the same dose. Talk to your doctor about the risks and benefits of taking Simvastatin on a higher dose.
Do not increase your dose or take this medication more than what is prescribed by your doctor. Your condition will not improve any faster, and the risk of serious side effects may be increased.
Avoid eating grapefruit or drinking grapefruit juice while using Simvastatin unless your doctor tells you otherwise. Grapefruit can increase the amount of Simvastatin in your bloodstream. Ask your doctor for more details.
Take Simvastatin regularly to get the most benefit from it. Take it about the same time each day to help you remember when to take a dose.
Continue taking Simvastatin even if you feel well. Most people with high cholesterol or triglycerides do not feel sick.
It is very important to follow your doctor’s advice about diet and exercise. It may take up to 4 weeks before you get the full benefit of this medication.
The usual dose of Simvastatin is once daily. Your dose is based on your medical condition, response to the medication, age, and other medications that you taking, especially medications to lower cholesterol.
Your doctor has prescribed this medication because he has deemed that the benefit to you is greater than the risk of side effects. Many people using this medication did not experience the serious side effects.
A very small number of people taking Simvastatin may have mild memory problems or confusion. If these effects occur, consult with your doctor.
Rarely, statins may cause or worsen diabetes. Talk to your doctor about the benefits and risks.
Simvastatin may rarely cause muscle problems that can at times lead to a very serious condition called rhabdomyolysis and autoimmune myopathy. Tell your doctor if you develop any of these symptoms during the treatment and if the symptoms persist after your doctor stops this drug: muscle pain, tenderness, or weakness, and signs of kidney problems.
This medication may rarely cause liver problems. If you notice any of the following rare but serious side effects, tell your doctor immediately: yellowing of the eyes or skin dark urine, persistent nausea or vomiting, and severe stomach or abdominal pain.
A very serious allergic reaction to this drug is rare. Seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including rash, itching or swelling, severe dizziness, or trouble breathing.
Before taking Simvastatin, tell your doctor if you are allergic to it, or if you have other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Share with your doctor your medical history before taking this medication, especially of liver or kidney disease, and alcohol use.
Tell your healthcare professional about the products you use before you undergo a surgical procedure.
Limit your consumption of alcoholic beverages while taking Simvastatin. Daily use of alcohol may increase your risk for liver problems, especially when combined with simvastatin.
Older adults may be more sensitive to the side effects of this drug, especially muscle problems.
Simvastatin must not be used during pregnancy. Simvastatin may harm an unborn baby. It is important that you prevent pregnancy while taking this medication. Consult your doctor for a reliable form of birth control while taking Simvastatin. If you become pregnant while you are taking Simvastatin, report it to your doctor immediately.
It is not known if Simvastatin passes into breast milk. Breastfeeding while using Simvastatin may possibly be risky to the infant. Consult your doctor before breastfeeding.
Drug interactions may change how medications work or increase their side effects. Share with your doctor a list of all the medications you are taking so he can determine if any of them will interact with Simvastatin.
Do not take any red yeast rice products while taking Simvastatin. Red yeast rice products may also contain a statin called lovastatin, which could increase your risk of serious muscle and liver problems.
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