Epiduo Gel

  • Antibacterial effect to treat acne
  • Benzoyl Peroxide + Adapalene
  • Helps the skin to heal and renew
From £35.00

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UK Medication

Dispensed by registered UK pharmacists

Buy Epiduo Gel UK | What is Epiduo?

Epiduo is a gel that is used in the treatment of moderate to severe acne. It contains two active ingredients; benzoyl peroxide and adapalene. These ingredients are both used to treat acne and they work in different ways.

Benzoyl peroxide is an antimicrobial agent and works by killing bacteria on the skin.

Adapalene belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.

How do I apply Epiduo?

Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.

Do not apply to broken skin.

How does Epiduo Gel work?

Epiduo Gel contains two active ingredients: adapalene and benzoyl peroxide. It is sometimes referred to as Epiduo 0.1% 2.5% Gel because of the strengths of both ingredients. There is also a higher strength gel that contains 0.3% of adapalene.

Adapalene is a drug that helps to reduce the blockage and inflammation of pores on the skin. Benzoyl peroxide works to kill bacteria that can cause acne. It also works by softening and peeling dead skin to prevent blockages and help prevent new spots from appearing.

How do I use Epiduo?

Epiduo is applied once daily, usually at night, just before bed. You should apply a thin layer of the gel to the affected area before bed. It's important to wash your face before application, then gently pat dry, so you are applying the gel to clean, dry skin. As well as washing your face, it's important to wash your hands thoroughly after application. This is because the benzoyl peroxide in the gel can bleach fabrics and hair. 

Epiduo Directions

Epiduo should be applied thinly and evenly on acne affected skin, making sure to avoid the eyes, nostrils, and lips. You should apply it once a day at bedtime. It should be applied to clean and dry skin.  

Always wash your hands before and after applying the gel.

How effective is Epiduo?

Most patients who use Epiduo will notice an excellent response. In trials, over 85% of patients had above a satisfactory response, while 71% had a good-excellent response. It can take up to 4 weeks to start to see a noticeable improvement in your acne. If you are not seeing results after 6 weeks, it's possible that Epiduo is not being effective in treating your acne. You can review your options with your local GP.

Epiduo Gel Side Effects

As with any medicine, Epiduo can cause side effects. Most people will tolerate Epiduo very well with no, or very minor side effects, like slight drying of skin. This can often be overcome by using a non-comedogenic moisturiser. 

However, like all medications, there are specific side effects to be aware of. The most common side effects with Epiduo gel are irritation of the skin, burning sensation to the affected area and eczema.

Epiduo Gel can cause your skin to become more sensitive to the sun. Avoid exposing your skin to the sun for too long and also avoid UV lamps during treatment.

See the patient information leaflet for a complete list of possible side effects.


Buy Epiduo Gel UK | Buy Epiduo Gel UK 

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